Some inhibitory effects of (−)-emetine on growth of Ehrlich ascites carcinoma

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Some inhibitory effects of (--)-emetine on growth of Ehrlich ascites carcinoma.

(-)-Emetine has little or no effect on O(2) consumption of Ehrlich ascites-cell suspensions or on the viability of transplanted Ehrlich ascites-tumour cells exposed to, or incubated with, the drug in vitro before inoculation into new-host mice. (-)-Emetine administered as a single injection to mice bearing Ehrlich ascites-tumour cells slows the growth rate of the tumour. The subcutaneous or int...

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Anl i-tumor sera are now being extensively used in investigations of the activities of neoplasms (e.g. 4-7, 9-13, 15). I t is already known (7), concerning their effects on the biochemical activities of tumors, that Ehrlich ascites carcinoma cells, treated with their antisera in the presence of comp]ement, lose their capacity to respire in the presence of glucose but not in the presence of succ...

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Phenethyl isothiocyanate Triggers Apoptosis, Combats Oxidative Stress and Inhibits Growth of Ehrlich Ascites Carcinoma Mouse Model

The aim of this study is to investigate the antitumor activity and possible molecular mechanism of Phenethyl isothiocyanate (PEITC) against Ehrlich ascites carcinoma in-vivo and in-vitro.In-vivo, ascetic fluid volume, body weight, serum malondialdehyde (MDA) level and total antioxidant capacity (TAC) were determined using Ehrlich ascites carcinoma (EAC) bearing mice. In-vitro, MTT assay was use...

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Phenethyl isothiocyanate Triggers Apoptosis, Combats Oxidative Stress and Inhibits Growth of Ehrlich Ascites Carcinoma Mouse Model

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 1974

ISSN: 0264-6021

DOI: 10.1042/bj1400087